Tobe, Shanan S, Kitchener, Andrew C and Linacre, Adrian (2009) Cytochrome b or cytochrome c oxidase subunit 1 for mammalian species identification – An answer to the debate. Forensic Science International: Genetics Supplement Series, 2 (1). pp. 306-307. ISSN 1875-1768

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Species identification for forensic purposes is being increasingly used, as the value of non-human evidence is realized. This requires the identification of the species before individual analysis can take place. Traditionally the cytochrome b (cyt b) gene was used for species identification, but in 2003 the cytochrome c oxidase subunit 1 (CO1) gene was introduced under the terminology ‘barcoding’. This started an ongoing debate as to which gene offers the best template for species identification (high inter-species variability and low intra-species variation). Sequence data from 236 mammals were compared with multiple sequence alignments for a large number of human, cow and dog samples. Comparisons were made based on the number of inter-species variations between the different species and the intra-species variation between members of the same species.

Item Type: Article
Additional Information: Progress in Forensic Genetics 13 — Proceedings of the 23rd International ISFG Congress
Uncontrolled Keywords: Species identification; Mammals; Cytochrome b (cyt b); Cytochrome c oxidase subunit 1 (COI); Inter-species variation; Intra-species variation
Subjects: Q Science > QH Natural history
Q Science > QH Natural history > QH426 Genetics
Q Science > QL Zoology
Theme: Understanding the natural world
Department: Natural Sciences
Related URLs:
Depositing User: Ruth Churchman
Date Deposited: 20 Jan 2011 15:21
Last Modified: 06 Aug 2013 14:12

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